| TOP2A's Target genes |
|
◢ TOP2A: Average |
| ◢ SRX6433370: Glioma |
◢ SRX6433371: Glioma |
◢ SRX11647358: HCT 116 |
◢ SRX11647359: HCT 116 |
◢ SRX7341865: hTERT RPE-1 |
◢ SRX7341866: hTERT RPE-1 |
◢ SRX4042129: KG-1 |
◢ SRX4042132: KG-1 |
◢ SRX4042135: KG-1 |
◢ SRX4042138: KG-1 |
◢ SRX4042141: KG-1 |
◢ SRX4042144: KG-1 |
◢ SRX6058767: T-47D |
◢ SRX6058768: T-47D |
◣ SRX6058769: T-47D |
◢ SRX6058770: T-47D |
| ◢ TOP2A: STRING |
| FRG2C |
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| UBA1 |
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| MTRNR2L2 |
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| MSH3 |
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| DHFR |
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| MTRNR2L1 |
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| FRG2 |
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| DUX4 |
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| MTRNR2L8 |
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| PLXDC2 |
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| COL23A1 |
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| CCDC200 |
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| RGPD2 |
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| RGPD1 |
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| PGK1 |
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| KIAA0319 |
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| TDP2 |
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| ACOT13 |
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| RABL6 |
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| FAM71F2 |
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| FOXD4 |
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| UBE3A |
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| MAMDC2 |
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| RANBP17 |
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| MTRNR2L9 |
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| CHMP6 |
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| YIF1B |
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| KANK1 |
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| USP17L5 |
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| USP17L30 |
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| USP17L29 |
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| USP17L28 |
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| USP17L27 |
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| USP17L26 |
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| USP17L25 |
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| USP17L24 |
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| OSGIN1 |
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| PMF1-BGLAP |
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| PMF1 |
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| ARMCX1 |
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| ZMYM2 |
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| CD70 |
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| ARHGAP39 |
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| GUCY2C |
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| ZNF584 |
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| CACNA1E |
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| CCDC33 |
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| DDX11 |
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| OSBP |
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| GAGE7 |
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| GAGE6 |
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| GAGE5 |
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| GAGE4 |
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| GAGE12I |
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| GAGE12F |
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| GAGE12B |
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| ZNF343 |
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| LINGO1 |
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| RANBP2 |
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| RAP1GAP2 |
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| CNTNAP5 |
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| ISLR2 |
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| CNOT3 |
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| PCBD2 |
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| ZNF484 |
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| MKI67 |
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| PPIP5K1 |
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| CKMT1B |
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| CEP20 |
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| SEMA7A |
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| MAN2C1 |
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| OR1J4 |
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| SF3A3 |
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| PEAR1 |
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| MTRNR2L10 |
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| OXTR |
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| MAP2 |
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| USP17L7 |
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| NBPF1 |
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| KCNQ1 |
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| ADPRS |
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| SPAAR |
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| PTPN9 |
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| UBL7 |
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| B4GALT7 |
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| PAXBP1 |
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| RPL26L1 |
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| PAIP2B |
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| RPL5 |
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| GNAI2 |
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| PLA2G4A |
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| APOBEC4 |
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| WDR74 |
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| LRRTM4 |
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| OSR1 |
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| CKMT1A |
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| ARID3B |
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| H2BC6 |
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| EEF1AKMT4-ECE2 |
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| EEF1AKMT4 |
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| ALG3 |
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≫ |
| TBL3 |
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| KCNJ9 |
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| SATB2 |
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| PLK3 |
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≫ |
| TMEM82 |
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|
|
|
|
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|
|
≫ |
| EFR3B |
↻ |
|
|
|
|
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|
|
|
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|
|
≫ |
| COMMD2 |
↻ |
|
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|
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|
|
≫ |
| ATAD3B |
↻ |
|
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|
|
≫ |
| PCARE |
↻ |
|
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|
|
≫ |
| ADGRL2 |
↻ |
|
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|
≫ |
| PERM1 |
↻ |
|
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|
≫ |
| CCDC150 |
↻ |
|
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|
|
≫ |
| ZBTB18 |
↻ |
|
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|
≫ |
| TRAIP |
↻ |
|
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|
|
≫ |
| HOXD13 |
↻ |
|
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|
|
≫ |
| HOXD12 |
↻ |
|
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≫ |
| WDR54 |
↻ |
|
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|
|
≫ |
| RBBP5 |
↻ |
|
|
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|
|
|
≫ |
| IQSEC1 |
↻ |
|
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|
|
≫ |
| HSPA6 |
↻ |
|
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|
|
≫ |
| C2orf81 |
↻ |
|
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|
≫ |
| MRGPRX3 |
↻ |
|
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|
≫ |
| GRAMD1C |
↻ |
|
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|
≫ |
| TRABD2A |
↻ |
|
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|
≫ |
| REN |
↻ |
|
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|
≫ |
| CFLAR |
↻ |
|
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|
≫ |
| MAB21L2 |
↻ |
|
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|
|
≫ |
| TERT |
↻ |
|
|
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|
|
≫ |
| CCR4 |
↻ |
|
|
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|
|
≫ |
| TEX46 |
↻ |
|
|
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|
|
≫ |
| RTN4 |
↻ |
|
|
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|
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|
|
≫ |
| KDM1A |
↻ |
|
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|
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≫ |
| THEM4 |
↻ |
|
|
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|
|
≫ |
| TAF13 |
↻ |
|
|
|
|
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|
|
|
|
≫ |
| PRSS48 |
↻ |
|
|
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|
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|
|
|
|
≫ |
| NCEH1 |
↻ |
|
|
|
|
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|
|
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|
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|
|
|
|
≫ |
| IRF2BP2 |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| GAGE1 |
↻ |
|
|
|
|
|
|
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|
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|
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|
|
|
|
≫ |
| ALKAL2 |
↻ |
|
|
|
|
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|
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|
|
|
|
≫ |
| PAFAH2 |
↻ |
|
|
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|
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|
|
|
|
≫ |
| AXDND1 |
↻ |
|
|
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|
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|
|
|
|
≫ |
| ODF3L1 |
↻ |
|
|
|
|
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|
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|
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|
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|
|
|
|
|
|
≫ |
| SPAG16 |
↻ |
|
|
|
|
|
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|
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|
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|
|
|
|
|
|
≫ |
| PHACTR4 |
↻ |
|
|
|
|
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|
|
|
|
≫ |
| IMP3 |
↻ |
|
|
|
|
|
|
|
|
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|
|
|
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|
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|
|
|
|
≫ |
| COMMD1 |
↻ |
|
|
|
|
|
|
|
|
|
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|
|
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|
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|
|
|
|
≫ |
| CCT4 |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| RRP9 |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| PARP3 |
↻ |
|
|
|
|
|
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|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| IQSEC3 |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| GTF3C3 |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| AGTR1 |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| PARL |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| PCBP3 |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| LGR6 |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| IGF2BP2 |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| TOMM40L |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| APOA2 |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| ACP6 |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| PRRT3 |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| AZIN2 |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| TRAPPC3 |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| TIGD1 |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| PPT1 |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| PACC1 |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| EIF4E2 |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| TBCE |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| RAB29 |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| LMNA |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| VPS72 |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| NUF2 |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| GP9 |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| GAGE12J |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| GAGE12G |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| GAGE12D |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| TMIGD3 |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| EPHX1 |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| ADORA3 |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| TRPC1 |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| STON1-GTF2A1L |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| PGD |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| NUDT4B |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| ATRIP |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| UBE2Q1 |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| PSMD4 |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| PHC3 |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| EPB41 |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| C1D |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| SH2D6 |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| MAP4K4 |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| EFHD1 |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| CSPG4 |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| SNX33 |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| CD200 |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| AGL |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| IPO13 |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| SCN3A |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| RIMS3 |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| MTERF1 |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| FOXD2 |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| TRAK1 |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| FAAP20 |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| CTNNA3 |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| CSRP1 |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| CACNA1S |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| ASCL5 |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| EIF2D |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| COPG1 |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| CLDN11 |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| MCM6 |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| ALK |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| SNX17 |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| HGD |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| GBA |
↻ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
≫ |
| EIF2B4 |
↻ |
|
|
|
|
|
|
|
|
|
|
|
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≫ |
| TRIP12 |
↻ |
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≫ |
| MATN1 |
↻ |
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≫ |
| LDAH |
↻ |
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≫ |
| FBXO36 |
↻ |
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≫ |
| DIPK1A |
↻ |
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≫ |
| DBI |
↻ |
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≫ |
| CTDSP1 |
↻ |
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≫ |
| CSMD2 |
↻ |
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≫ |
| CNIH4 |
↻ |
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≫ |
| C2orf76 |
↻ |
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≫ |
| C1orf94 |
↻ |
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≫ |
| ZFAND2B |
↻ |
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≫ |
| SNORC |
↻ |
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≫ |
| MYNN |
↻ |
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≫ |
| MOGAT1 |
↻ |
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≫ |
| LMAN2L |
↻ |
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≫ |
| ACTRT3 |
↻ |
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≫ |
| TSGA10 |
↻ |
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≫ |
| RPS27 |
↻ |
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≫ |
| RAB13 |
↻ |
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≫ |
| PLEKHM2 |
↻ |
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≫ |
| NFU1 |
↻ |
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≫ |
| LRBA |
↻ |
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≫ |
| INPP1 |
↻ |
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≫ |
| C2orf15 |
↻ |
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≫ |
| ANGPTL7 |
↻ |
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≫ |
| ZZZ3 |
↻ |
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≫ |
| SLC26A6 |
↻ |
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≫ |
| GPD1L |
↻ |
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≫ |
| DHDDS |
↻ |
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≫ |
| ACTR3 |
↻ |
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≫ |
| TMCC2 |
↻ |
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≫ |
| NUP133 |
↻ |
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≫ |
| NEURL3 |
↻ |
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≫ |
| CERS2 |
↻ |
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≫ |
| CEP63 |
↻ |
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≫ |
| ANXA9 |
↻ |
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≫ |
| ANAPC13 |
↻ |
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≫ |
| GYG1 |
↻ |
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≫ |
| ACVR1C |
↻ |
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≫ |
| GORASP2 |
↻ |
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≫ |
| SIDT1 |
↻ |
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≫ |
| LMOD1 |
↻ |
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≫ |
| SSNA1 |
↻ |
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≫ |
| CDC73 |
↻ |
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≫ |
| ANAPC2 |
↻ |
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≫ |
| ANAPC1 |
↻ |
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≫ |
| GAREM1 |
↻ |
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≫ |
| CZIB |
↻ |
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≫ |
| USP13 |
↻ |
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≫ |
| SH3D19 |
↻ |
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≫ |
| ICA1L |
↻ |
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≫ |
| EVX2 |
↻ |
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≫ |
| SH3BP4 |
↻ |
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≫ |
| GOLGA8B |
↻ |
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≫ |
| FEV |
↻ |
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≫ |
| UBE2Q2 |
↻ |
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≫ |
| PVRIG |
↻ |
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≫ |
| SGO2 |
↻ |
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≫ |
| PRKAB2 |
↻ |
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≫ |
| CHD1L |
↻ |
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≫ |
| WDFY1 |
↻ |
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≫ |
| UBE4B |
↻ |
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≫ |
| TRIM67 |
↻ |
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≫ |
| RPS29 |
↻ |
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≫ |
| GPR155 |
↻ |
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≫ |
| PDGFRA |
↻ |
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≫ |
| MRPL53 |
↻ |
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≫ |
| TMEM63A |
↻ |
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≫ |
| POMZP3 |
↻ |
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≫ |
| SLC33A1 |
↻ |
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≫ |
| IL18R1 |
↻ |
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≫ |
| TMC7 |
↻ |
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≫ |
| STX12 |
↻ |
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≫ |
| GAGE8 |
↻ |
|
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≫ |
| GAGE2E |
↻ |
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≫ |
| GAGE2D |
↻ |
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≫ |
| GAGE13 |
↻ |
|
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≫ |
| CNOT10 |
↻ |
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≫ |
| SOAT1 |
↻ |
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≫ |
| PBXIP1 |
↻ |
|
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≫ |
| TTC26 |
↻ |
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≫ |
| CAMTA1 |
↻ |
|
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≫ |
| AGAP2 |
↻ |
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≫ |
| SCNM1 |
↻ |
|
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≫ |
| PRR30 |
↻ |
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≫ |
| PREB |
↻ |
|
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≫ |
| PLCD4 |
↻ |
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≫ |
| LYSMD1 |
↻ |
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≫ |
| IFI6 |
↻ |
|
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≫ |
| MARCHF9 |
↻ |
|
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≫ |
| GATA4 |
↻ |
|
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≫ |
| CDK4 |
↻ |
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≫ |
| EIF3C |
↻ |
|
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≫ |
| DAG1 |
↻ |
|
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≫ |
| WDSUB1 |
↻ |
|
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≫ |
| RPS8 |
↻ |
|
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|
≫ |
| NR5A2 |
↻ |
|
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|
≫ |
| ZFP69B |
↻ |
|
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≫ |
| XRCC2 |
↻ |
|
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|
≫ |
| MFN2 |
↻ |
|
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≫ |
| PPOX |
↻ |
|
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≫ |
| CREB5 |
↻ |
|
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≫ |
| POLM |
↻ |
|
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|
≫ |
| NMNAT1 |
↻ |
|
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|
≫ |
| LZIC |
↻ |
|
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|
≫ |
| FAM3C |
↻ |
|
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|
≫ |
| ZNF148 |
↻ |
|
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≫ |